For patients with high PD-L1 expression, pembrolizumab showed a favorable trend, but the pre-specified statistical difference was not reached.
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International expert consensus on immunotherapy for early-stage non-small cell lung cancer.
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Subgroup analysis revealed that patients with EGFR mutations (n=73) showed a trend favoring pembrolizumab (HR: 0.44; 95% CI: 0.23–0.84), which was more prominent than that in patients without EGFR mutations (n=434) (HR: 0.78; 95% CI: 0.59–1.05) ( 29 ).