The optimal anticoagulation strategy for COVID-19, prophylactic or therapeutic?: a meta-analysis, trial sequential analysis, and meta-regression of more than 27,000 participants.

Emerg Crit Care Med · 2022 · PMC9555559 · PMID 37521812

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did not reach statistical significanceno p-value reported

In a small subgroup of critically ill patients in all studies or RCTs only, I-TA tended to increase the rate of major bleeding, but it did not reach statistical significance, compared with PA.

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