showed a trendP <0.05
Despite this, relative abundance comparisons of individual microbes at the ASV level showed a trend towards increased abundance ( P <0.05, P FDR = 0.74; Supplementary Table 2 ) of Bacteroides vulgatus , Holdemanella biformis and Lachnospiraceae spp. in the fecal microbiome ( Supplementary Figure 2C ).