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P2X7 purinergic receptor plays a critical role in maintaining T-cell homeostasis and preventing lupus pathogenesis.

Front Immunol · 2022 · PMC9556828 · PMID 36248812

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The Table S1 presents cytokines, such as IL-12p70 or IL-18, whose levels were found higher in B6/ lpr - p2x7 KO sera than parental strains or MRL/ lpr sera, but this trend of overexpression failed to reach statistical significance due to high inter-individual variability.

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