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Evaluation of the additive effect of interferon α 2b with monthly intravitreal injection of bevacizumab in refractory diabetic macular edema.

Int J Retina Vitreous · 2022 · PMC9558405 · PMID 36224669

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Based on our finding, IFN causes an additional CMT reduction in comparison to Bevacizumab monotherapy, and the reduction was more prominent in the IFN sub-tenon injection group (− 117 μm in sub-tenon group at month 3 vs − 49 μm in IFN drop, and − 36 μm in Bevacizumab monotherapy); however, it can be attributed to the relatively small sample size of the study in detecting the difference in data with wide standard deviation that this difference did not reach statistical significance.

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