The other six antimanic drugs, namely paliperidone, valproate, asenapine, eslicarbazepine, brexpiprazole, and topiramate did not reach statistical significance in their variability of improvement of manic symptoms compared to placebo.
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Variability and efficacy in treatment effects on manic symptoms with lithium, anticonvulsants, and antipsychotics in acute bipolar mania: A systematic review and meta-analysis.
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