Prognostic and Predictive Significance of Stromal Tumor-Infiltrating Lymphocytes (sTILs) in ER-Positive/HER2-Negative Postmenopausal Breast Cancer Patients.

Cancers (Basel) · 2022 · PMC9564297 · PMID 36230767

Europe PMC DOI

hedged sentences

0.1400

closest p · 2.8× alpha

0.1400

boldest claim

The sentences

borderline significantp = 0.14not close (p > 0.1)

Patients with higher score of the immune response module IMMUNE1 showed no significant tamoxifen benefit (HR (95% CI) = 0.67 (0.34–1.33)), whereas patients with low IMMUNE1 score did (HR (95% CI) = 0.35 (0.20–0.61)) with borderline significant interaction test in univariate ( p = 0.14) and multivariable analyses ( p = 0.09) ( Figure 6 E,F).

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did not reach statistical significanceno p-value reported

Although these results might suggest that high TILs could be coupled with treatment resistance, the test for interaction did not reach statistical significance.

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