both the benign nodule and the control group, with a significant trend of increasing plasma 8-isoprostane levels from pulmonary controls to subjects with lung benign nodules to subjects with lung cancer.
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Quantification of Plasma 8-Isoprostane by High-Performance Liquid Chromatography with Tandem Mass Spectrometry in a Case-Control Study of Lung Cancer.
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The sentences
Considering that there may be significant cross-reactivity with the multiple isomers of COX-derived prostaglandins, ELISA may not be the most precise method [ 19 ].