Long-Lasting Nociplastic Pain Modulation by Repeated Administration of Sigma-1 Receptor Antagonist BD1063 in Fibromyalgia-like Mouse Models.

Int J Mol Sci · 2022 · PMC9569697 · PMID 36233233

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did not reach statistical significanceno p-value reported

As for pregabalin, RIM6-PGB did not significantly differentiate from either RIM6-Veh ( p = 0.276) or RIM6-BD1063 ( p = 0.270), indicating that its effect on astrogliosis did not reach statistical significance.

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