Proof-of-Principle Study Suggesting Potential Anti-Inflammatory Activity of Butyrate and Propionate in Periodontal Cells.

Propionate and acetate also showed a trend towards anti-inflammatory activity but did not reach the level of significance.

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Reduced expression of IL6 and CXCL2 was noted when RAW 264.7 cells were exposed to butyric acid, while propionate and acetate failed to reach significance ( Figure 1 ).

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