Catheter Ablation versus Medical Therapy of Atrial Fibrillation in Patients with Heart Failure: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Compared to patients on MT, those undergoing CA showed a trend towards a reduction in the composite endpoint (RR 0.59; (95% CI: 0.33–1.05); p = 0.07; I 2 = 17%) ( Figure 6 c) and a significative reduction in HF hospitalizations (RR 0.57; (95% CI: 0.41–0.78); p = 0.0006; I 2 = 0%) and AF recurrence (RR 0.35; (95% CI: 0.22–0.55); p < 0.00001; I 2 = 82%).

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