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Off-label and investigational drugs in the treatment of alcohol use disorder: A critical review.

Front Pharmacol · 2022 · PMC9574013 · PMID 36263121

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While the primary study outcome, percentage of heavy drinking days, was lower, it did not reach statistical significance upon ABT-436 treatment compared to placebo, whereas the secondary endpoint, the percentage of abstinent days, significantly increased with ABT-436 treatment.

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