Barely Significant
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The proteolysis targeting chimera GMB-475 combined with dasatinib for the treatment of chronic myeloid leukemia with BCR::ABL1 mutants.

Front Pharmacol · 2022 · PMC9574342 · PMID 36263131

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showed a trendno p-value reported
The results showed that although GMB-475 showed a trend of reducing the tumor burden ( Figure 3C,D ) and prolonging the survival of the CML mouse model ( Figure 3B ), its effect was limited and not statistically significant.

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