Tranexamic Acid Dosing in Craniosynostosis Surgery: A Systematic Review with Meta-analysis.

38 However, this study focuses on minimally invasive procedures which pose less overall risk, and any analysis on outcomes of open procedures did not reach statistical significance. 38 Another study analyzing TXA in pediatric scoliosis surgery patients concludes that high dose (50 mg/kg) TXA was more effective than low dose (10 mg/kg) in reducing blood loss and transfusion. 39 In that article, the population studied was markedly older than the population in our cohort.

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