The quantitative analyses of the neuronal somata immunostaining did not reach statistical significance ( Supplementary Fig. 6B ), while the analyses of the perisomata region showed a decrease in the transfected neurons (siTDP-43) of the immunofluorescence intensity of NOS1AP, GluN2B, PSD93/Chapsyn-110 and PSD95/SAP90 ( Fig. 8B ) proteins.
← all excerpts
NOS1AP is a novel molecular target and critical factor in TDP-43 pathology.
1
—
—