Serological responses to human virome define clinical outcomes of Italian patients infected with SARS-CoV-2.

Interestingly, while we found antibodies reactive to a median of 9 viral epitopes per sample in the Brescia cohort, there was an elevation of total reactive antibodies to known viruses in COVID-19 patients compared to non-COVID-19 patients, although it did not reach statistical significance (Figure 1 B).

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We also found an increasing trend in antibody production to the spike protein over time during hospitalization (Figure 2 H).

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