In addition, the effect of TRPV1 expression remained highly significant in correlation with overall survival after adjustments for age, sex, smoking status and clinical stage, suggesting that TRPV1 can be an independent prognostic predictor (Supplementary Table S 1 ).
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Overexpressed transient receptor potential vanilloid 1 (TRPV1) in lung adenocarcinoma harbours a new opportunity for therapeutic targeting.
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The sentences
The trends did not reach statistical significance which may due to the degree of variance caused by small sample volume of metastasis positive patients.