Heterologous prime-boost BCG with DNA vaccine expressing fusion antigens Rv2299c and Ag85A improves protective efficacy against <i>Mycobacterium tuberculosis</i> in mice.

Flow cytometry indicated that boosting increased the percentages of CD8 + T cells producing IFN-γ, TNF-α, and IL-17A in response to PPD in the lung, and IFN-γ, TNF-α, and IL-2 in the spleen but the differences did not reach statistical significance ( Supplementary Figure S7 ).

also in 111,027 other papers