Barely Significant
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Effects of high-dose opioid analgesia on survival, pain relief, quality of life and adverse drug reactions in cancer and neuropathic pain patients: a retrospective cohort study in real-world clinical practice.

Ann Transl Med · 2022 · PMC9577752 · PMID 36267754

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showed a trendno p-value reported
Although there is no statistical difference, quality of life showed a trend of improvement compared with before treatment.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.