Barely Significant
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IL-10 producing regulatory B cells are decreased in blood from smokers and COPD patients.

Respir Res · 2022 · PMC9578234 · PMID 36253785

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In naive B cells (Bna), IRF4 levels where significantly decreased upon CSE exposure whereas HIF-1α levels tended to increase upon CSE exposure, but the latter did not reach statistical significance.

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