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D2R signaling in striatal spiny neurons modulates L-DOPA induced dyskinesia.

iScience · 2022 · PMC9579025 · PMID 36274959

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Notably, following acute L-DOPA, 6-OHDA iMSN-D2RKO mice showed a trend toward increased of c-Fos + cells and of pERK 42/44 intensity/cell as compared to equally treated 6-OHDA WT (p > 0.05; Figures S5 A–S5C).

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