Monocyte-derived peritoneal macrophages protect C57BL/6 mice against surgery-induced adhesions.

Front Immunol · 2022 · PMC9583908 · PMID 36275765

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did not reach statistical significanceno p-value reported

It has previously been suggested that injection of an artificial CCR2 ligand (recombinant MCP-1) to attract monocytes to the peritoneal cavity at the time of surgery can reduce adhesion formation in mice, however the effect did not reach statistical significance ( 11 ) and MCP-1/CCL2 is not specific for monocytes but also attracts memory T lymphocytes and natural killer (NK) cells ( 37 ).

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