High co-expression of immune checkpoint receptors PD-1, CTLA-4, LAG-3, TIM-3, and TIGIT on tumor-infiltrating lymphocytes in early-stage breast cancer.

World J Surg Oncol · 2022 · PMC9587596 · PMID 36271406

Europe PMC DOI

hedged sentence

0.0860

closest p · 1.7× alpha

0.0860

boldest claim

The sentences

did not reach statistical significancep = 0.086so close (0.05 < p ≤ 0.1)

Interestingly, only TIM-3 expression on CD8 + and CD16 + CD56 dim NK cells in PBLs and TILs showed positive correlations, but these associations did not reach statistical significance ( p = 0.086 and p = 0.072, respectively) (Table 2 ).

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