Evaluating the role of type 2 diabetes mellitus in rotator cuff tendinopathy: Development and analysis of a novel rat model.

Front Endocrinol (Lausanne) · 2022 · PMC9588920 · PMID 36299460

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

an increasing trendno p-value reported

Compared with the non-diabetic group, the expression levels of genes involved in tissue repair (COL1A), tenogenesis (TNC, TNMD, SCX), osteogenesis (RUNX2), and chondrogenesis (SOX9) of the supraspinatus tendon of the rotator cuff showed an increasing trend after induction of type 2 diabetes, where the TNC mRNA expression levels of the supraspinatus tendon were significantly increased in the 2-week group after induction of type 2 diabetes (p < 0.05), and the COL1A1 mRNA expression levels of the supraspinatus tendon were significantly increased in the 4-week group after induction of type 2 diabetes (p < 0.001).

also in 63,971 other papers

showed a trendno p-value reported

In the current study, gene expression analysis confirmed that COL1A1 and TNC in the supraspinatus tendon of the rotator cuff in type 2 diabetic rats continued to increase in the first four weeks, after which they showed a trend of continuously decreased expression, indicating that there is a continuous remodeling process in the supraspinatus tendon in response to persistent microdamage caused by hyperglycemic conditions.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.