The proportion of PD1 − CTLA4 + cells that produced CA-MS HIV RNA upon stimulation tended to be lower than in the double-negative subset, but this comparison did not reach statistical significance (p = 0.063; Figure 5 D).
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Memory CD4<sup>+</sup> T cells that co-express PD1 and CTLA4 have reduced response to activating stimuli facilitating HIV latency.
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0.0630
0.0630