Meta-analysis of the prognostic value of circulating tumor cells in gastrointestinal cancer.

Medicine (Baltimore) · 2022 · PMC9592416 · PMID 36281182

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did not reach statistical significanceno p-value reported

In addition, we determined the effect of CTCs status on OS and PFS in terms of treatment and found that for patients undergoing surgery, the detection of CTCs at baseline was associated with an increased risk of poor prognosis (OS: HR = 2.25, 95% CI = 1.51–4.75, P = .200, I 2 = 32.0%; PFS: HR = 3.69, 95% CI = 1.99–6.87, P = .020, I 2 = 70.0%), although the finding did not reach statistical significance.

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