Barely Significant
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Starting to have sexual intercourse is associated with increases in cervicovaginal immune mediators in young women: a prospective study and meta-analysis.

Elife · 2022 · PMC9596159 · PMID 36281966

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As shown in Figure 5AB , immune mediator concentrations were generally higher post-first sex in this subset of samples, but the effects were smaller and all but one (IL-12p70) failed to reach statistical significance.

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