Centenarians consistently present a younger epigenetic age than their chronological age with four epigenetic clocks based on a small number of CpG sites.

nonagenarian’s vs centenarians, or to the sex of the oldest parent (NC mother vs NC father) did not showed clear evidence of DNAmage differences, despite of a slightly significant p -value (0.0460) for the first comparison with Bekaert clock ( Supplementary Figure 3A , 3B ).

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