Barely Significant
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Defective ryanodine receptor N-terminus inter-subunit interaction is a common mechanism in neuromuscular and cardiac disorders.

Front Physiol · 2022 · PMC9597452 · PMID 36311249

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Although NT R169Q+Q168R and NT R169Q+M399R tetramer formation did not reach statistical significance relative to NT R169Q , it was also not significantly different to NT WT ( Table 2 ).

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