Effects of the Phenethylamine 2-Cl-4,5-MDMA and the Synthetic Cathinone 3,4-MDPHP in Adolescent Rats: Focus on Sex Differences.

Corticosterone plasma levels were also increased in females that underwent saline self-administration training as compared to the corresponding male group, although this trend did not reach statistical significance (+81%; p = 0.08). 3.3. rVTA Dopamine Neurons Recordings In order to quantitatively evaluate the effects of 2-Cl-4,5-MDMA or 3,4-MDPHP on the spontaneous firing activity of DA neurons in rVTA slices obtained from both males and females, spike discharge was recorded in the cell-attached configuration.

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