Interleukin-8 in Colorectal Cancer: A Systematic Review and Meta-Analysis of Its Potential Role as a Prognostic Biomarker.

Biomedicines · 2022 · PMC9599846 · PMID 36289899

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highly significantno p-value reported

Sensitivity analysis demonstrated a highly significant correlation with outcome for circulating, but not for tissue-detected, IL-8.

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did not reach statistical significanceno p-value reported

The association between high IL-8 expression and worse PFS was confirmed by analyzing only the three studies reporting adjusted PFS data (675 patients, Figure 4 B), although it did not reach statistical significance using a random effect model.

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