Macrophage Phenotypes and Gene Expression Patterns Are Unique in Naturally Occurring Metabolically Healthy Obesity.

Int J Mol Sci · 2022 · PMC9604193 · PMID 36293536

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

a trend toward significancep = 0.06so close (0.05 < p ≤ 0.1)

Tissue MCP-1 also demonstrated a trend toward significance by health status ( p = 0.06), where unhealthy animals had higher levels ( Supplementary Table S5 ).

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did not reach statistical significanceno p-value reported

Differences in specific macrophage subtypes did not reach statistical significance ( Supplementary Table S2 ), highlighting the importance of the M2/M1 macrophage ratio in local and systemic inflammation.

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