Epigenetic Manipulation Induced Production of Immunosuppressive Chromones and Cytochalasins from the Mangrove Endophytic Fungus <i>Phomopsis asparagi</i> DHS-48.

Mar Drugs · 2022 · PMC9605342 · PMID 36286441

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moderately significantno p-value reported

Additionally, compound 5 showed significant in vitro cytotoxicity against human cancer cell lines Hela, with an IC 50 value of 5.8 μM, and showed moderately significant in vitro cytotoxicity against human cancer cell lines HepG2, with an IC 50 value of 59 μM ( Table 4 ), respectively, which was comparable with the positive controls adriamycin and fluorouracil.

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