Efficacy and Safety of a Brain-Penetrant Biologic TNF-α Inhibitor in Aged APP/PS1 Mice.

Pharmaceutics · 2022 · PMC9612380 · PMID 36297637

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did not reach statistical significanceno p-value reported

TfRMAb-TNFR treatment significantly reduced insoluble high-molecular-weight Aβ oligomers, and a similar trend was seen with etanercept, but these values did not reach statistical significance.

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