Comorbidity between lung cancer and COVID-19 pneumonia: role of immunoregulatory gene transcripts in high <i>ACE2</i>-expressing normal lung.

Ther Adv Med Oncol · 2022 · PMC9618916 · PMID 36324736

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xpression in an univariable analysis [ Figure 1(d) to ( k )], Table 1 shows that, when entered into a multivariable analysis, only TNM stage > 1 (p = 0.04) and high TOX (p = 0.02) expression correlated independently with high versus low ACE2 expression in normal lung tissue; High CD8A and high ICOS showed a trend for association with high ACE2 (CD8A p = 0.06, ICOS p = 0.08 multivariable).

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