White matter integrity and functional connectivity in adolescents with a parental history of substance use disorder.

Second, the psychological impulsivity profiles of our two adolescent groups were very similar, with marginally significant differences reported only in the BIS-11 attentional scale but no differences in the BIS/BAS.

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We reported the results for the FH+ and FH- comparison under p < 0.05, which was corrected for multiple comparisons using FDR, as well as exploratory analysis at a more lenient level (uncorrected p < 0.05) to reveal differences across groups approaching significance. 2.6.2 Resting-state fMRI data We compared functional connectivity of brain regions within and between resting state networks using a region-of-interest analyses in Conn toolbox ( Whitfield-Gabrieli and Nieto-Castanon, 2012 ).

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