Microneedle-based ocular drug delivery systems - recent advances and challenges.

Beilstein J Nanotechnol · 2022 · PMC9623140 · PMID 36348935

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a significant trendno p-value reported

In order to minimize tissue damage, reduce the disruption of the membrane continuity, eliminate the risk of pathogens infections, ensure faster regeneration and improve the overall safety, the tendency to minimize the size of the needles became a significant trend and led to introduction of microneedles [ 92 – 98 ].

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