Clonal lineage tracing reveals mechanisms skewing CD8+ T cell fate decisions in chronic infection.

J Exp Med · 2023 · PMC9623343 · PMID 36315049

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approached significanceno p-value reported

GP276-specific SHP-1 cKO CD8 + T cells exhibited a significantly reduced proportion of progenitor cells and a ∼30% reduction in the frequency of exhausted cells that approached significance, while effector cell frequency was significantly increased nearly twofold ( Fig.

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