Barely Significant
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A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.

EMBO J · 2022 · PMC9627671 · PMID 36215696

2
hedged sentences
0.0490
closest p · 1.0× alpha
0.0490
boldest claim

The sentences

nominally significantP = 0.049actually significant
The observed association for rs350845, which is linked to higher SIRT6 levels is nominally significant ( P = 0.049).

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a slight trendno p-value reported
The A313S allele showed a slight trend toward stronger suppression but did not show a significant improvement over the wild‐type SIRT6 when assessed for the 3′ bias.

also in 4,078 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.