Preventing type 1 diabetes in late-stage pre-diabetic NOD mice with insulin: A central role for alum as adjuvant.

Within the CD8 + T cell compartment in mice receiving Ins+alum, there were trends for a reduced frequency of EM cells (P = 0.06) ( Supplementary Figure 3F ), contrasting an increased frequency of naïve cells ( Supplementary Figure 3H ), however these differences did not reach statistical significance.

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