The differential role of the lipid raft-associated protein flotillin 2 for progression of myeloid leukemia.

While deficiency of FLOT2 led to a significant reduction of adhesion to HS-5 stromal cells, there was a strong trend toward restoration of adhesion when sh FLOT2 + K562 cells were treated with ML141 ( P = .0216) ( Figure 7G ).

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