Abrogation of neutrophil inflammatory pathways and potential reduction of neutrophil-related factors in COVID-19 by intravenous immunoglobulin.

Front Immunol · 2022 · PMC9632428 · PMID 36341409

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Similarly, IL-8, a strong chemoattractant and activator of neutrophils also showed a trend down over time, but in this case there was a significant difference between COVID-19 and healthy plasma ( Figures 3G, H ), which aligns to our previous findings and others associating increased IL-8 in the severity of COVID-19 ( 8 ).

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