Anti-inflammatory and pro-anabolic effects of 5-aminosalicylic acid on human inflammatory osteoarthritis models.

J Orthop Translat · 2023 · PMC9633873 · PMID 36381242

Europe PMC DOI

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showed a trendno p-value reported

Although not significant, 20 mM 5-ASA showed a trend in down-regulation of IL-8 and up-regulation of ACAN and COL2A1 gene expression.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.