Correlation of Markers of Inflammation with Hormonal, Metabolic Parameters, Insulin Resistance and Adiposity Indices in First-Degree Relatives of Patient with Polycystic Ovary Syndrome.

Although brothers of PCOS had a higher prevalence of MetS yet, it did not reach statistical significance.[ 23 ] In another Indian study by Shabir et al . at 46% of first-degree relatives of PCOS had Metabolic syndrome.[ 25 ] In the study by Shabir et al ., maximum participants (PCOS women as well as family members) had dyslipidaemia in the form of low HDL and high triglycerides.[ 25 ] Increased levels of LDL cholesterol along with MetS in affected sisters of women with PCOS were reported by Sam et al .[ 5 39 ] We found the mean HOMA IR was 2.35 ± 0.76, showing a mild presence of IR.

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