Sleep deprivation and hippocampal ripple disruption after one-session learning eliminate memory expression the next day.

Proc Natl Acad Sci U S A · 2022 · PMC9636927 · PMID 36279444

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0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

marginally significantP = 0.058so close (0.05 < p ≤ 0.1)

4 D ) did not show any changes across conditions, but ripples showed marginally significant higher coupling with PPC than PFC spindles (rmANOVA brain area P = 0.058, F 1,2 = 15.7).

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showed a trendno p-value reported

Our study enabled a comparable investigation in rodents; delta and spindle events were detected as well as coupled delta-spindle events in the PFC and PPC, and showed that while all three showed a trend toward an increase after all behavioral conditions relative to Baseline, this was not statistically significant ( Fig. 4 A – C , rmANOVA for each event type all P > 0.14).

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