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Induction of pulmonary HLA-G expression by SARS-CoV-2 infection.

Cell Mol Life Sci · 2022 · PMC9637071 · PMID 36334153

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A statistically significant, inverse expression of HLA-G-regulating miRNAs and HLA-G protein was detected for miR-744-5p ( p = 0.0063) and for miR-152 ( p = 0.036), which bind to the CDS and the 3ʹ UTR of the HLA-G mRNA, respectively, whereas the expression of miR-548q ( p = 0.0982) and miR-148B ( p = 0.2302) did not reach statistical significance (Fig. 2 ).

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