Glycosyltransferases EXTL2 and EXTL3 cellular balance dictates heparan sulfate biosynthesis and shapes gastric cancer cell motility and invasion.

J Biol Chem · 2022 · PMC9637574 · PMID 36181793

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showed a trendno p-value reported

Structural analyses showed a trend for increased HS disaccharide content in EXTL2 KO cells, in comparison with WT, while in EXTL3 KO cells HS disaccharides were not detected ( Fig. 3 A ).

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