The interplay of dopamine metabolism abnormalities and mitochondrial defects in the pathogenesis of schizophrenia.

Transl Psychiatry · 2022 · PMC9640700 · PMID 36344514

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Furthermore, they did a meta-analysis of 818 genes combining the PGC-SCZ2 and iPSYCH samples and revealed 104 nominally significant and nine significant genes, confirming the involvement of the nuclear-encoded mitochondrial genes in schizophrenia [ 115 ].

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