Except for fluoroquinolones, the DOT per 1,000 PD for carbapenems, piperacillin-tazobactam, and cefepime showed a trend toward a significant increase (Supplementary Fig. 1 ).
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Impact of coronavirus disease 2019 (COVID-19) pandemic on antimicrobial consumption and antimicrobial resistance at a small, local hospital in Japan.
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The sentences
Moreover, the incidence of ESBL-E and CAUTI also showed an increasing trend, reaffirming the importance of appropriate antimicrobial use and infection prevention programs during the pandemic.