Genetically predicted telomere length and Alzheimer's disease endophenotypes: a Mendelian randomization study.

Alzheimers Res Ther · 2022 · PMC9641781 · PMID 36345036

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nominally significantno p-value reported

However, stratified analysis by PRS-AD suggested a protective effect of inherited longer TL on core AD pathology, with longer TL nominally significant associated with lower levels of p-tau among individuals at high genetic predisposition of AD.

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